E4 - Exercise to counteract the metabolic burden of sleep restriction with Nicholas Saner - Show notes



Main paper that we discuss:

Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and diurnal rhythms
	https://www.sciencedirect.com/science/article/pii/S2212877820301848#!

								
Other papers that we refer to in our discussion:

Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects (Schrauwen-Hinderling et al. 2007)
	https://link.springer.com/article/10.1007/s00125-006-0475-1

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity (Meex et al. 2010)
	https://diabetesjournals.org/diabetes/article/59/3/572/13809/Restoration-of-Muscle-Mitochondrial-Function-and

Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity (van Moorsel et al. 2016)
	https://www.sciencedirect.com/science/article/pii/S2212877816300758?via%3Dihub

Day-night rhythm of skeletal muscle metabolism is disturbed in older, metabolically compromised individuals (Wefers et al. 2020)
	https://www.sciencedirect.com/science/article/pii/S2212877820301241?via%3Dihub

Impact of sleep debt on metabolic and endocrine function (Spiegel et al. 1999)
	https://www.sciencedirect.com/science/article/pii/S0140673699013768?casa_token=z2nO4CK4FcIAAAAA:EJmoSOZyEzwZSgiFhrHxBfli28M_qik3EDqa23wP5WWy0w32lq3Svua-BoB9IuUnMeqAI5nx_Uw
	
Effects of sleep deprivation on the activity of selected metabolic enzymes in skeletal muscle ( Vondra et al. 1981)
	https://link.springer.com/article/10.1007/BF00422481

Even with recovery sleep, insulin sensitivity is still impaired:
Ad libitum Weekend Recovery Sleep Fails to Prevent Metabolic Dysregulation during a Repeating Pattern of Insufficient Sleep and Weekend Recovery Sleep (Depner et al. 2019)
	https://www.sciencedirect.com/science/article/pii/S0960982219300983

Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trial (Savikj et al. 2019)
	https://link.springer.com/article/10.1007/s00125-018-4767-z

Distal skin temperature changes in response to light exposure:
High sensitivity of human melatonin, alertness, thermoregulation, and heart rate to short wavelength light (Cajochen et al. 2015)
	https://academic.oup.com/jcem/article/90/3/1311/2836588

Frieder’s recent paper on light exposure and diurnal rhythms in skin temperature: 
The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of day (Harmsen et al. 2022)
	https://link.springer.com/article/10.1007/s00125-021-05643-9

Diurnal Blood Pressure Variations Are Associated with Changes in Distal–Proximal Skin Temperature Gradient (Kräuchi et al. 2012)
	https://www.tandfonline.com/doi/full/10.3109/07420528.2012.719961

Warm feet promote the onset of sleep (Kräuchi et al. 1999)
	https://www.nature.com/articles/43366

Nick's Review with Brad Schoenfield:
The effects of time of day-specific resistance training on adaptations in skeletal muscle hypertrophy and muscle strength: A systematic review and meta-analysis (Grgic et al. 2019)
	https://www.tandfonline.com/doi/full/10.1080/07420528.2019.1567524?casa_token=Nceg32sjid4AAAAA%3AkS5mCHz_i1d4-0Ihk2OnGw1dw5A7M1oQiYZvYR20wQTU7uy6O6subnF0ScBOEOpW_g8r5UznGEvyuA


Nick Saner on Social Media:
Twitter: @NickSaner
Email: nicholas.saner@baker.edu.au